7 Reasons Men Die First

POPULAR CULTURE MAY paint men as the stronger sex, but from the moment a boy is born, his life is more likely than his sister's to be cut short. Across national and cultural boundaries, men die an average of seven years earlier than women; the disparity in the United States is approximately five years. In a new book, Why Men Die First, Marianne Legato, a specialist in gender-specific medicine at Columbia University, explains: They're genetically and biologically fragile to start with, she says, and societal norms that encourage and even demand risky behavior by men put them at risk. Still, Legato told U.S. News, men and their families can push back. She highlighted seven reasons why males die prematurely—and seven actions they can take to prolong their time.

1. Males are burdened with natural genetic deficits.

While every cell in a woman's body has two large X chromosomes, men have one X and one smaller Y chromosome; the Y is half the size. The "spare" X chromosomes allow women's bodies to compensate when faced with damage in ways that men's cells cannot. In addition, mutations are three to six times more likely in a Y chromosome than an X chromosome. This genetic deficit could be part of the reason why miscarriages, infections, birth defects, cancers, and many other health problems strike males especially hard. 2. The womb is more treacherous for boys.

Baby boys are one-and-a-half to two times more likely to die at birth than girls. A weaker immune system, a tendency for immature lung development, inadequate blood flow to male fetuses, and high vulnerability to maternal stresses seem to be the culprits. Brain hemorrhages, congenital malformations, pneumonia, and urinary tract infections are all more common among male newborns. 3. Males are more likely to have developmental disorders.

An article published in the British Medical Journal notes that a variety of disorders—including reading delays, deafness, autism, ADHD, blindness, seizure disorders, hyperactivity, clumsiness, stammering, and Tourette's syndrome are three to four times more common in boys than girls. There are 10 males for every female with Asperger's syndrome, a mild form of autism. 4. They're biologically more prone to risky behavior.

Slower development of the area of the brain that governs judgment makes males—especially adolescents—more likely than girls to die in accidents. According to a National Safety Council statistics, males were involved in 82 percent of accidental deaths associated with firearms, 87 percent of bicycle-related fatalities, nearly double the number of poisoning deaths, and almost four times as many homicides in 2004. Likewise, in 2006 they were in 81 percent of fatal crashes involving drunken driving. 5. A "suck-it-up" culture means men often languish with depression.

Although women are more likely to make suicide attempts, the ratio of men to women who actually kill themselves is nearly 4 to 1. For men ages 20 to 24, fully 15 percent of all deaths are suicides. 6. Men choose more dangerous occupations.

The bulk of sailors, firefighters, police officers, construction workers, and farmers are men. Of the 5,734 fatalities that occurred on the job in 2005, men were the victims in the vast majority—5,328. And men still do the vast majority of the fighting during military conflicts. 7. Coronary artery disease strikes men early.

Estrogen seems to protect women from heart disease until they are well into midlife, but it is common for symptoms to begin in men by the age of 35. Making matters worse, men have naturally low levels of protective HDL cholesterol. The result: Between 70 percent and 89 percent of all sudden cardiac events occur in men, and men die three times more frequently of coronary artery disease than women.